\r\n
Alpha One can help build lean muscle and strength through a variety of pathways, including some very unique and exciting ones that are unlike anything you’ve ever tried before.<\/p>\r\n
(cAMP) Cyclic adenosine monophosphate:<\/span><\/strong><\/p>\r\n cAMP is a very important cellular messenger that has been shown to perform key functions in the regulation of skeletal muscle mass and function.<\/p>\r\n cAMP elevating agents have been reported to promote significant increases in protein synthesis and reductions in catabolic process, which means that cAMP has both anabolic and anti-catabolic properties<\/p>\r\n Olfactory Receptors:<\/span><\/strong><\/p>\r\n Olfactory Receptors represent a novel pathway that can lead to increases in cAMP in places we want it to occur, such as muscle and fat cells.<\/p>\r\n mTOR\/Akt & Improved Protein Synthesis:<\/span><\/strong><\/p>\r\n When researchers studied the muscle cells from mice that had been given a-Cedrene, they saw that it had increased the activity of anabolic signaling molecules such as mTOR and Akt.<\/p>\r\n Myostatin:<\/span><\/strong><\/p>\r\n Research on mice has shown that a-Cedrene decreased Myostatin.<\/p>\r\n Myostatin is a myokine that limits muscle growth in humans and other animals, especially in skeletal muscles used for movement.<\/p>\r\n As one study concluded:<\/strong><\/p>\r\n α-Cedrene is a promising agent that may be used to enhance the mass and strength of skeletal muscle.<\/p>\r\n One very exciting aspect of one of the rodent studies on a-Cedrene is that it is one of few ingredients that has been shown in a study to cause muscle gain and fat loss at the same time.<\/p>\r\n The study showed that supplementation with a-Cedrene did not make the mice heavier. However, it made them more muscular and stronger.<\/p>\r\n In laymen’s terms, this means that the mice maintained their body weight by building muscle and losing fat at the same time.<\/p>\r\n Let’s take a moment to really understand and fully appreciate the significance of that:<\/p>\r\n They were losing fat and building muscle at the same time!<\/strong><\/p>\r\n This is an aspect of Alpha One that we weren’t expecting to be nearly as pronounced as it was for a lot of people!<\/p>\r\n By the time we had let some testers try Alpha One, we already had labels printed. The feedback was so good for pumps that we actually tossed the original labels and had new ones printed to mention the pumps and muscle fullness aspects.<\/p>\r\n Here is some feedback from real people that tried them:<\/p>\r\n “Whatever is in those softgels is brutal for pumps. Did a high rep arm workout and I swear I thought my arms were going to split through the skin if I bent them.”<\/em><\/p>\r\n “Most of my workouts aren’t conducive to pumps, but I switched it up for the session today and I laid on the floor with my arms outstretched because I had to tell myself they wouldn’t tear if I bent them.”<\/em><\/p>\r\n “Whatever these softgels are, they’re awesome. They remind me of the pumps back when I could use X-Gels. They’re a different type of pump than a pump product, like a denser rock hard pump.”<\/em><\/p>\r\n Alpha One works via a multi-faceted approach towards building muscle and losing fat, including a new and novel pathway compared to other natural anabolic and recomposition ingredients.<\/p>\r\n a-Cedrene, the active ingredient in Alpha One works through several unique methods of action, with two very exciting ones being cAMP and the olfactory receptors.<\/p>\r\n The olfactory receptors are most commonly thought of as being connected to our sense of smell but are also found in many different areas of the body including skeletal muscle, the liver, heart, brain, and fat cells and performing some very unique and important functions.<\/p>\r\n Olfactory Receptors represent a novel pathway that can lead to increases in cAMP in places we want it to occur, such as muscle and fat cells.<\/p>\r\n One way that a-Cedrene exerts its powerful anabolic and recomposition effects is due to its ability to act as an agonist to the OR10J5 olfactory receptor, which leads to the activation of the cyclic AMP response element binding protein (CREB) pathway and leads to potent increases in cAMP in target tissues such as skeletal muscle and fat cells.<\/p>\r\n This same pathway also supports improved glucose tolerance, enhanced insulin sensitivity, and enhanced fat lipolysis (breakdown).<\/p>\r\n Cyclic adenosine monophosphate (cAMP) is an important cellular messenger that has been shown to perform many key functions in the body including playing an important role in fat loss, body-composition, and the regulation of skeletal muscle mass.<\/p>\r\n The term ‘second messenger’ was coined with the discovery of cAMP. The term is used to identify a small molecule generated intracellularly upon cell stimulation and capable of regulating downstream cellular events.<\/p>\r\n cAMP is a very important secondary messenger for signal transduction at the cellular level and has been shown to perform key functions in the regulation of skeletal muscle mass and function.<\/p>\r\n cAMP elevating agents have been reported to promote significant increases in protein synthesis and reductions in catabolic process, which means that cAMP has both anabolic and anti-catabolic properties.<\/p>\r\n cAMP promotes the mobilization of glucose and fatty acid reserves, and increasing levels of cAMP can support increased levels of lipolysis (the breakdown of fat).<\/p>\r\n At least one study found a correlation between fat-cell size and cAMP concentration in obese non-diabetic patients.<\/p>\r\n cAMP has been shown to mimic the healthy aging effects of calorie restriction by reducing adipose tissue size, lowering cholesterol and triglyceride levels, and increasing SIRT1 and SIRT3 levels.<\/p>\r\n cAMP plays an important role in many biological processes as a second messenger, and cAMP has been shown in studies to improve aging related phenotypes by increasing levels of Sirtuins, which mimic the effects of calorie restriction. Experiments in vitro showed that cAMP binds to SIRT1 and SIRT3 and increased their activity. These findings suggest that cAMP may support healthy aging and is a good candidate to mimic calorie restriction.<\/p>\r\n Increasing cyclic adenosine monophosphate (cAMP) levels may cause stomach discomfort in some individuals. This is rare, but possible with any cAMP increasing supplements.<\/p>\r\n If individuals experience stomach discomfort with any cAMP increasing supplements, it is suggested that they take the supplements with food as that resolves it in most people. It is also suggested that the individual stay with the minimum suggested dose and not increase the dosage until the stomach discomfort subsides.<\/p>\r\n Alpha One can be taken with Anabolic Effect, M-Test, Cloma-Plex, Nattybolic, Super Swole, or a variety of other CEL products for even more hardcore results.<\/p>\r\n<\/div>","gtin12":"891192002510","image":["https:\/\/siteimgs.com\/10017\/item\/alpha-one-rendering-fro_1725544284-0.jpg","https:\/\/siteimgs.com\/10017\/item\/alpha-one-supp-facts_1725544290-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/34464\/competitive-edge-labs-alpha-one-60-softgels.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/34464\/competitive-edge-labs-alpha-one-60-softgels.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Competitive Edge Labs Anabolic Effect - 180 Capsules","sku":"CG026","description":" Decimate Your Genetic Limitations<\/p> The Landscape of Natural Anabolics Just Changed Anabolic + Anti-Catabolic + Endurance Enhancing + Fat Burning + More 7 High End Active Ingredients 4 Licensed Branded Ingredients ..... Backed by Clinically Researched Key Ingredients<\/p> Anabolic Effect doesn\u2019t just raise the bar for natural anabolics, it takes the bar and beats all the existing preconceived notions upside then head with it and then completely redefines the category itself.<\/p> Anabolic Effect contains 7 high end natural anabolic ingredients including 4 licensed branded ingredients and clinically researched key ingredients and brings them together to create the ultimate natural anabolic powerhouse.<\/p> Anabolic + Anti-Catabolic + Endurance Enhancing + Fat Burning = The Gold Standard of Natural Anabolics Actually, Gold Standard may sound better but Anabolic Effect would probably be better described as the platinum standard because platinum is stronger, denser, and more valuable than gold.<\/p> Korean Mistletoe is a semi-parasitic plant that grows on various trees and has been used for centuries to treat a variety of ailments. It has been researched for a diverse range of potential benefits and is believed to have immunostimulatory, anti-diabetic, and anti-obesity properties, and much more. Of particular interest to athletes and fitness enthusiasts is that Korean Mistletoe has been reported to increase lean muscle mass, strength, and overall exercise capacity.<\/p> Recent research has focused on Korean Mistletoe Extract for use as a treatment for the prevention and reversal of muscle wasting conditions. The research on Korean Mistletoe Extract has been exceptional and could be quite beneficial for athletes. It has been shown to regulate gene expression related to muscle atrophy (muscle breakdown) and muscle hypertrophy (muscle growth) and improve endurance by stimulating mitochondrial activity.<\/p> Korean Mistletoe having been shown to not only prevent muscle atrophy but also promote hypertrophy is significant because it means that Korean Mistletoe not only prevents muscle breakdown but also increases muscle growth. In studies, mice that were fed Korean Mistletoe for 4 weeks showed increases in muscle mass and grip strength. Researchers indicated multiple factors leading to this result including the AKT\/mTOR pathway. The AKT\/mTOR pathway is a signaling pathway recognized as the major pathway regulating protein synthesis. Due to the mice showing increases in muscle and greatly increased strength, the researchers determined that Korean Mistletoe is anabolic as it directly leads to larger and stronger muscles. In addition to increases in muscle and strength, the mice also showed incredible increases in endurance and exercise capacity making Korean Mistletoe an ideal option for strength, endurance, and fitness athletes.<\/p> Korean Mistletoe has also been shown in studies to increase endurance and decrease fatigue through increasing mitochondrial oxygen consumption and increased expression of PPARy. Notable examples included increases of up to 212% in swim tests on mice and in one test mice being fed Korean Mistletoe extract ran twice as far as their counterparts resulting in an incredible 100% increase in endurance. (Don\u2019t take us wrong here, we are just conveying the study information but do realize that that is far too good to be true for it to directly translate over into humans at the same %\u2019s; but even transferring over at a fraction of the effectiveness could lead to incredible results).<\/p> The last study that we want to bring attention to in this write up is related to fat loss. In one 15 week study on mice, two groups were fed a high fat diet with one group also being fed Korean Mistletoe Extract. At the end of the study, the mice fed the Korean Mistletoe Extract were shown to have 20% less bodyfat than the control group. Researchers found that Korean Mistletoe Extract increases thermogenesis and nearly tripled the amount of UCP1 (uncoupling protein 1), a thermogenic molecule related to the burning of subcutaneous and visceral fat.<\/p> This is an incredible level of fat burning potential for something so anabolic. In summary, Korean Mistletoe Extract shows promising potential to be anabolic, anti-catabolic, endurance enhancing, and to increase fat burning. Anabolic Effect provides 2,000 mg. Korean Mistletoe Extract per serving.<\/p> Eriobotrya Japonica contains a variety of natural anabolic components that may be beneficial to those looking to build lean muscle, increase strength, burn fat, & improve endurance and athletic performance. These include some very well-known names such as Epicatechin, Ferulic Acid, Caffeic Acid, Ursolic Acid, Tormenic Acid, Ellagic Acid, and more. Studies have shown Eriobotrya Japonica to increase the expression of certain myogenic genes and also activate the AKT\/mTOR pathway and therefore promote muscle protein synthesis and lean muscle gains. In studies, Eriobotrya Japonica has been shown to prevent muscle atrophy (muscle wasting\/muscle loss) and to increase muscle hypertrophy (muscle growth) which also makes it ideal for lean muscle retention while dieting.<\/p> Rehmannaie Radix has several active compounds may be useful for building lean muscle, strength, and improving endurance, athletic performance, and fat loss. However, the main two we are going to focus on are Catalpol and to a lesser extent, Loganin.<\/p> Catalpol has been referred to by some as the closest one can get to natural gene doping due to its effects on erythropoietin (EPO), vascular endothelial growth factor (VEGF), insulin like growth factor type 1 (IGF-1), endorphins, and more.<\/p> Erythropoietin (EPO) increases red blood cells which can in turn carry more oxygen to the muscles and lead to increases in overall performance and increases in VO2 max, overall power output, increased endurance, delayed fatigue, improved recovery, and more. These boosts give athletes a huge competitive advantage and EPO has been used illegally by athletes for decades to increase performance. It is most commonly associated with cycling because of the high number of cyclists that have been caught using EPO. What if you could naturally increase EPO? Of course, not to the degree that comes with illicit use, but that may still provide noticeable results in improved performance?<\/p> Loganin is a lesser known and lesser emphasized constituent of Rehmannaie Radix Extract. However, if Catalpol wasn\u2019t such an extraordinary ingredient, Loganin itself may be an ingredient worth featuring on its own. It is an iridoid glycoside and can be derived from several sources but is present in high quantities in Rehmannaie Radix. Loganin has the potential to be a fascinating anabolic agent in its own right and is currently being studied for muscle atrophy. In addition, Loganin seems to possess anti-inflammatory, antioxidant, glucose lowering, and muscle protective benefits. Loganin is thought to work by upregulating the AKT\/mTOR pathway and increasing IGF-1. Loganin has also been shown in animal studies to increase lean muscle, strength, and protein synthesis.<\/p> While many of the ingredients in Anabolic Effect may have potent synergistic effects with one another, the combination of Rehmannaie Radix and S7 may be particularly interesting due to Catalpol\u2019s possible effects on EPO and S7 having been shown to increase nitric oxide levels by 230% through stimulating the body\u2019s own natural production of nitric oxide. This could lead to an abundance of oxygen rich red blood cells being pumped through wide open blood vessels to hard working muscles.<\/p> PrimaVie is a clinically proven high quality purified Shilajit extract from the Himalayas that contains 50% Fulvic Acid and over 40 other trace minerals and has been shown in studies to significantly increase free and total testosterone levels, as well as improve physical performance and reduce fatigue. In one human trial, Shilajit was able to markedly enhance the extracellular matrix gene expression responsible for skeletal muscle adaptation, making it one of the only ingredients to augment the effect of exercise in this manner.<\/p> In another study involving 60 infertile men, Shilajit supplementation was able to improve sperm count by over 60%, improve sperm motility by nearly 40%, and increase levels of testosterone by 23.5% through a reduction inn circulating free radicals. To further back this up, another study involving 75 males demonstrated a 20% increase in total testosterone and a 19% increase in free testosterone.<\/p> Shilajit has been used for centuries in Ayurvedic medicine to support male sexual health, energy, vitality, cognitive health, rejuvenation and more.<\/p> In short, ActiGin is designed to help you train harder, longer, and recover more effectively.<\/p> The human body already produces nitric oxide as a vasodilator, signaling the blood vessels to relax, thus increasing blood flow and delivering more oxygen, fuel, and other key nutrients to the muscles.<\/p> S7 is a blend of 7 plant-based ingredients that has been clinically shown to increase nitric oxide (NO) levels by 230%. S7 is very unique in that it works differently than other nitric oxide boosters on the market by triggering the body to increase its own internal nitric oxide production.<\/p> Anabolic Effect contains 50 mg. of S7, the dosage used in the clinical studies showing the 230% nitric oxide increase.<\/p> AstraGin is a natural patented ingredient complex comprised of highly fractionated Astragalus membranaceus and Panax notoginseng and created using pharmaceutical grade extraction and processing technology and designed to help enhance nutrient absorption.<\/p> In short, AstraGin is designed to help make sure you properly absorb the other great nutrients in Anabolic Effect for maximum results.<\/p> Anabolic Effect The Ultimate Natural Anabolic Powerhouse<\/p> *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.<\/p>","gtin12":"891192002329","image":["https:\/\/siteimgs.com\/10017\/item\/competitive-edge-labs-ana_2045-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/29014\/competitive-edge-labs-anabolic-effect-180-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/29014\/competitive-edge-labs-anabolic-effect-180-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Competitive Edge Labs Anabolic Effect - 2 x 180 Capsule Bottles TWINPACK","sku":"CG2026","description":" Decimate Your Genetic Limitations<\/p> The Landscape of Natural Anabolics Just Changed Anabolic + Anti-Catabolic + Endurance Enhancing + Fat Burning + More 7 High End Active Ingredients 4 Licensed Branded Ingredients \u2026.. Backed by Clinically Researched Key Ingredients<\/p> Anabolic Effect doesn\u2019t just raise the bar for natural anabolics, it takes the bar and beats all the existing preconceived notions upside the head with it and then completely redefines the category itself.<\/p> Anabolic Effect contains 7 high end natural anabolic ingredients including 4 licensed branded ingredients and clinically researched key ingredients and brings them together to create the ultimate natural anabolic powerhouse.<\/p> Anabolic + Anti-Catabolic + Endurance Enhancing + Fat Burning = The Gold Standard of Natural Anabolics Actually, Gold Standard may sound better but Anabolic Effect would probably be better described as the platinum standard because platinum is stronger, denser, and more valuable than gold.<\/p> Korean Mistletoe: Korean Mistletoe is a semi-parasitic plant that grows on various trees and has been used for centuries to treat a variety of ailments. It has been researched for a diverse range of potential benefits and is believed to have immunostimulatory, anti-diabetic, and anti-obesity properties, and much more. Of particular interest to athletes and fitness enthusiasts is that Korean Mistletoe has been reported to increase lean muscle mass, strength, and overall exercise capacity.<\/p> Recent research has focused on Korean Mistletoe Extract for use as a treatment for the prevention and reversal of muscle wasting conditions. The research on Korean Mistletoe Extract has been exceptional and could be quite beneficial for athletes. It has been shown to regulate gene expression related to muscle atrophy (muscle breakdown) and muscle hypertrophy (muscle growth) and improve endurance by stimulating mitochondrial activity.<\/p> Korean Mistletoe having been shown to not only prevent muscle atrophy but also promote hypertrophy is significant because it means that Korean Mistletoe not only prevents muscle breakdown but also increases muscle growth. In studies, mice that were fed Korean Mistletoe for 4 weeks showed increases in muscle mass and grip strength. Researchers indicated multiple factors leading to this result including the AKT\/mTOR pathway. The AKT\/mTOR pathway is a signaling pathway recognized as the major pathway regulating protein synthesis. Due to the mice showing increases in muscle and greatly increased strength, the researchers determined that Korean Mistletoe is anabolic as it directly leads to larger and stronger muscles. In addition to increases in muscle and strength, the mice also showed incredible increases in endurance and exercise capacity making Korean Mistletoe an ideal option for strength, endurance, and fitness athletes.<\/p> Korean Mistletoe has also been shown in studies to increase endurance and decrease fatigue through increasing mitochondrial oxygen consumption and increased expression of PPARy. Notable examples included increases of up to 212% in swim tests on mice and in one test mice being fed Korean Mistletoe extract ran twice as far as their counterparts resulting in an incredible 100% increase in endurance. (Don\u2019t take us wrong here, we are just conveying the study information but do realize that that is far too good to be true for it to directly translate over into humans at the same %\u2019s; but even transferring over at a fraction of the effectiveness could lead to incredible results).<\/p> The last study that we want to bring attention to in this write up is related to fat loss. In one 15 week study on mice, two groups were fed a high fat diet with one group also being fed Korean Mistletoe Extract. At the end of the study, the mice fed the Korean Mistletoe Extract were shown to have 20% less bodyfat than the control group. Researchers found that Korean Mistletoe Extract increases thermogenesis and nearly tripled the amount of UCP1 (uncoupling protein 1), a thermogenic molecule related to the burning of subcutaneous and visceral fat.<\/p> This is an incredible level of fat burning potential for something so anabolic. In summary, Korean Mistletoe Extract shows promising potential to be anabolic, anti-catabolic, endurance enhancing, and to increase fat burning. Anabolic Effect provides 2,000 mg. Korean Mistletoe Extract per serving.<\/p> Eriobotrya Japonica Extract: Eriobotrya Japonica contains a variety of natural anabolic components that may be beneficial to those looking to build lean muscle, increase strength, burn fat, & improve endurance and athletic performance. These include some very well-known names such as Epicatechin, Ferulic Acid, Caffeic Acid, Ursolic Acid, Tormenic Acid, Ellagic Acid, and more. Studies have shown Eriobotrya Japonica to increase the expression of certain myogenic genes and also activate the AKT\/mTOR pathway and therefore promote muscle protein synthesis and lean muscle gains. In studies, Eriobotrya Japonica has been shown to prevent muscle atrophy (muscle wasting\/muscle loss) and to increase muscle hypertrophy (muscle growth) which also makes it ideal for lean muscle retention while dieting.<\/p> Rehmannaie Radix Extract: Rehmannaie Radix has several active compounds that may be useful for building lean muscle, strength, and improving endurance, athletic performance, and fat loss. However, the main two we are going to focus on are Catalpol and to a lesser extent, Loganin.<\/p> Catalpol has been referred to by some as the closest one can get to natural gene doping due to its effects on erythropoietin (EPO), vascular endothelial growth factor (VEGF), insulin like growth factor type 1 (IGF-1), endorphins, and more.<\/p> Erythropoietin (EPO) increases red blood cells which can in turn carry more oxygen to the muscles and lead to increases in overall performance and increases in VO2 max, overall power output, increased endurance, delayed fatigue, improved recovery, and more. These boosts give athletes a huge competitive advantage and EPO has been used illegally by athletes for decades to increase performance. It is most commonly associated with cycling because of the high number of cyclists that have been caught using EPO. What if you could naturally increase EPO? Of course, not to the degree that comes with illicit use, but that may still provide noticeable results in improved performance.<\/p> Loganin is a lesser known and lesser emphasized constituent of Rehmannaie Radix Extract. However, if Catalpol wasn\u2019t such an extraordinary ingredient, Loganin itself may be an ingredient worth featuring on its own. It is an iridoid glycoside and can be derived from several sources but is present in high quantities in Rehmannaie Radix. Loganin has the potential to be a fascinating anabolic agent in its own right and is currently being studied for muscle atrophy. In addition, Loganin seems to possess anti-inflammatory, antioxidant, glucose lowering, and muscle protective benefits. Loganin is thought to work by upregulating the AKT\/mTOR pathway and increasing IGF-1. Loganin has also been shown in animal studies to increase lean muscle, strength, and protein synthesis.<\/p> While many of the ingredients in Anabolic Effect may have potent synergistic effects with one another, the combination of Rehmannaie Radix and S7 may be particularly interesting due to Catalpol\u2019s possible effects on EPO and S7 having been shown to increase nitric oxide levels by 230% through stimulating the body\u2019s own natural production of nitric oxide. This could lead to an abundance of oxygen-rich red blood cells being pumped through wide-open blood vessels to hard-working muscles.<\/p> PrimaVie Shilajit Extract (50% Fulvic Acid): PrimaVie is a clinically proven high quality purified Shilajit extract from the Himalayas that contains 50% Fulvic Acid and over 40 other trace minerals and has been shown in studies to significantly increase free and total testosterone levels, as well as improve physical performance and reduce fatigue. In one human trial, Shilajit was able to markedly enhance the extracellular matrix gene expression responsible for skeletal muscle adaptation, making it one of the only ingredients to augment the effect of exercise in this manner.<\/p> In another study involving 60 infertile men, Shilajit supplementation was able to improve sperm count by over 60%, improve sperm motility by nearly 40%, and increase levels of testosterone by 23.5% through a reduction in circulating free radicals. To further back this up, another study involving 75 males demonstrated a 20% increase in total testosterone and a 19% increase in free testosterone.<\/p> Shilajit has been used for centuries in Ayurvedic medicine to support male sexual health, energy, vitality, cognitive health, rejuvenation and more.<\/p> In short, ActiGin is designed to help you train harder, longer, and recover more effectively.<\/p> S7: The human body already produces nitric oxide as a vasodilator, signaling the blood vessels to relax, thus increasing blood flow and delivering more oxygen, fuel, and other key nutrients to the muscles.<\/p> S7 is a blend of 7 plant-based ingredients that has been clinically shown to increase nitric oxide (NO) levels by 230%. S7 is very unique in that it works differently than other nitric oxide boosters on the market by triggering the body to increase its own internal nitric oxide production.<\/p> Anabolic Effect contains 50 mg of S7, the dosage used in the clinical studies showing the 230% nitric oxide increase.<\/p> AstraGin: AstraGin is a natural patented ingredient complex comprised of highly fractionated Astragalus membranaceus and Panax notoginseng and created using pharmaceutical grade extraction and processing technology and designed to help enhance nutrient absorption.<\/p> In short, AstraGin is designed to help make sure you properly absorb the other great nutrients in Anabolic Effect for maximum results.<\/p> Anabolic Effect - The Ultimate Natural Anabolic Powerhouse<\/p>","gtin12":"891192002329","image":["https:\/\/siteimgs.com\/10017\/item\/anab-twin_1680812270-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/33004\/competitive-edge-labs-anabolic-effect-180-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"76.98","url":"https:\/\/www.dpsnutrition.net\/i\/33004\/competitive-edge-labs-anabolic-effect-180-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Competitive Edge Labs Api-Plex - 90 Capsules","sku":"CG030","description":" Anabolic Phytonutrient & Muscle Builder\r\nNovel Muscle Building Supplement<\/p> Api-Plex Highlights\/Supports:<\/p> Ask Yourself a Few Questions:\r\nDo you want to build lean muscle and strength?\r\nDo you want to improve body-composition and workout performance?\r\nDo you like the idea of supplementing with an ingredient that has so many potential benefits that a series of articles could be written about it?\r\n^^^ If so, Apigenin may be a supplement of interest to you.<\/p> The quest for muscle and performance gains has led researchers for years to look for natural compounds that can enhance muscle protein synthesis, boost muscle growth, enhance recovery, and improve performance. Over the years, scientists have come across a number of exciting natural anabolic compounds, but rarely one that has such a broad range of potential benefits as Apigenin.<\/p> Lean Muscle & Strength\r\nImproved Workout Performance\r\nIncreases in Stamina & Endurance\r\nIncreased Protein Synthesis\r\nImproved Insulin Resistance\r\nSupports Cortisol Modulation\r\nEnhanced IGF-1 and IGF-2 Levels\r\nAnabolic & Anti-Catabolic Properties\r\nPotential Anti-Aromatase\/Anti-Estrogenic Properties\r\n& More<\/p> Positive Mood\r\nProstate Health\r\nBlood Pressure Support\r\nCardiovascular Health\r\nAnti-inflammatory Support\r\nImproved Insulin Resistance\r\nPositive Effects on Autophagy\r\nImproved Sense of Well-Being\r\nNeuroprotective & Cardioprotective Properties\r\nNumerous Potential Anti-Aging & Longevity Benefits\r\n& More<\/p> Api-Plex For Those That Want to\u2026.Maximize Every Possible Bit of Their Natural Muscle Growth Potential What is Apigenin?<\/p> Apigenin is a natural flavonoid found in parsley, celery, chamomile, and citrus fruits that is similar to Quercetin, Hesperidin, Luteolin, and Kaempferol. However, even though its structure is very similar to these compounds, Apigenin has some very different effects in the body than those related substances.<\/p> Apigenin has a natural anabolic effect, as first discovered by researchers at the Korea Food Research Institute.<\/p> In the initial study that led to Apigenin\u2019s popularity for building muscle, scientists began experimenting with his flavone with mice and the mice receiving the Apigenin had significant muscle mass gains over the mice not receiving it. The greater the dosage of Apigenin the mice took, the larger the Quad increase!<\/p> Apigenin, even before the research showing its natural anabolic benefits, was already regarded as a very exciting compound due to its wide variety of overall benefits including its anti-inflammatory benefits as well as its potential prostate, neuroprotective, and cardioprotective properties. However, of particular interest to many researchers is Apigenin\u2019s potential anti-cancer benefits, which have made Apigenin the subject of many studies around the world.<\/p> Another very exciting aspect of Apigenin is its ability to enhance autophagy. Autophagy is a natural cellular mechanism by which by which the cells in our body degrade unnecessary or damaged components within the cell. The process of autophagy helps maintain normal functioning (homeostasis) in the cell. (If you\u2019re familiar with what defragging a computer means, think of that as a good comedic analogy to this process by the cells).<\/p> Apigenin has also been studied for a wide variety of other potential benefits including its anti-inflammatory, antioxidant, anti-aromatase, cardiovascular, and antibacterial properties, and more.<\/p> Muscle Building, Longevity, Anti-Aging Properties, & More\r\nWhat are flavones\/flavonoids?<\/p> Flavonoids\/flavones are bioactive compounds in plants that exert a wide range of biological effects. They fulfill many different functions in plants and the ones in Apigenin have been shown to offer a wide range of potential beneficial effects, including beneficial effects on improved athletic performance and helping to build and preserve muscle tissue.<\/p> Apigenin Study Relating to Muscle Growth and Performance Enhancement:\r\nScientists at the Korea Food Research Institute began experimenting with Apigenin in Mice and found that the mice receiving Apigenin had significant muscle mass gains of the mice not receiving it.<\/p> This study was split into a control group, a lower dose Apigenin group, and a higher dose Apigenin group. Researchers observed that the greater the dose of Apigenin that the mice took, the larger the quadriceps increase.<\/p> The estimated human equivalent to the dosages used in these studies were 20 mg. For the lower dosage group and 40 mg. For the higher dosage group.<\/p> There were a number of mechanisms of action noted in the studies, including:<\/p> Apigenin increased the production of contractile muscle protein (MHC).\r\nIncreases in the anabolic hormones IGF-1 and IGF-2.\r\nIncreases in PGC-1-alpha, a signal molecule that stimulates cells to manufacture more mitochondria.\r\nTriggering of anabolic pathways by activating the enzyme protein arginine methyltransferase-7 (Prmt7) \u2013 shown after in vitro research with C2C12 muscle cells.<\/p> Some things mentioned in researcher\u2019s conclusions were:<\/p> \u201cWe found that apigenin increases quadriceps muscle weight in mice and increases their running distance on an accelerating treadmill.\u201d\r\n\u201cThese events are attributable to upregulation of the Prmt7-PGC-1-alpha-GPR56 signaling pathway.\u201d\r\n\u201cWe also found that apigenin induces myogenic differentiation by regulating Prmt7-p38-myoD and the Akt-S6K1 pathway in C2C12 cells.\u201d\r\n\u201cThese results suggest that apigenin could be used as a functional food to prevent muscle loss and enhance muscle function.\u201d\r\nWe found during our own research on this that the links may change depending on the one provided to this study, but can be found by doing a google search with the terms \u2018Korea Food Research\u2019 and \u2018Apigenin\u2019.<\/p> As mentioned above, Apigenin was shown in studies to increase protein synthesis and the same researchers observed substantial muscle growth. These researchers noticed observable increases in muscle size and function, including increased thickness in the quadriceps muscles and increased running performance.<\/p> When compared to the control group, the higher the dose of Apigenin, the greater the increase in muscle mass. It is also important to note that these increases in muscle size came without increases in total body weight or subcutaneous fat gain.<\/p> In addition to increased protein synthesis, researchers noted that these muscle gains were due to enhanced myogenic differentiation, increases in the nucleus ratio in muscle fibers (myotubes), and increased phosphorylation of p38 MAPK. This is significant because p38 MAPK is a major regulator or skeletal muscle development.<\/p> This makes Apigenin an extremely attractive potential natural muscle building compound.<\/p> In studies on mice, after 7 weeks of Apigenin supplementation, researchers let mice run to exhaustion on a treadmill. The ones that had received Apigenin performed better than the ones in the control group. Rodent studies don\u2019t always correlate directly to humans but real world feedback on Apigenin supports the theory that Apigenin may significantly improve stamina and athletic performance in many individuals.<\/p> Apigenin has a lot of potential as an anti-aging & longevity supplement for a variety of reasons, many of which are discussed above or below in this write up and range from its potential overall anti-cancer benefits to its cardiovascular, cardioprotective, and neuroprotective benefits, and more.<\/p> In addition to the ones listed above, Apigenin has the potential to be a potent anti-catabolic (muscle preserving) supplement to help fight the muscle wasting effects of aging.<\/p> The importance of maintaining strength and muscle mass is often overlooked in the scope of most anti-aging supplements, but it can be extremely important for a wide variety of reasons including supporting immune system health, injury prevention, improved mobility & stability, improved self-esteem, and more.<\/p> The mTOR pathway is the pathway in the body that drives muscle protein synthesis. It can be activated by a number of means including by amino acids (leucine), insulin, and various growth factors.<\/p> Apigenin has been reported to significantly increase muscle protein synthesis via increased phosphorylation of several key components in the mTOR pathway, including Akt, S6K1, and 4E-BP1.<\/p> Apigenin also supports the increased expression of protein Prmt7, a potent regulator of muscle mass.<\/p> As mentioned above, there are a number of growth factors capable of stimulating mTOR in the body. Insulin-like growth factor (IGF) is one of these growth factors. Both subtypes of IGF, both IGF-1 and IGF-2, contribute to regulating skeletal muscle development and regeneration (building muscle).<\/p> Apigenin has been shown to support the up-regulatory expression of both IGF-1 and IGF-2 in studies<\/p> Apigenin has been researched for its anti-aromatase and estrogen-modulating properties; including being studied for its effects on aromatase mRNA gene expression.<\/p> Aromatase is the enzyme that catalyzes the conversion of testosterone to estradiol (an estrogen). By supporting the reduction of both aromatase and 17\u03b2-hydroxysteroid dehydrogenase (17\u03b2-HSD), Apigenin may also support an increase in natural testosterone levels.<\/p> Apigenin\u2019s unique ability to inhibit 17\u03b2-HSD is very rare and is something that has only been accomplished naturally with very few other flavonoids.<\/p> Cortisol is the body\u2019s primary stress hormone released when we encounter threatening and stressful situations. While some cortisol is necessary and even beneficial, chronically elevated levels of cortisol can lead to significant reductions in testosterone, loss of muscle tissue, and fat storage.<\/p> Apigenin may have a beneficial effect on reducing cortisol levels. In cell culture studies using human adrenal cells, reductions in cortisol levels were noted when exposed to Apigenin. Also, Apigenin may have an inhibitory effect on a key cortisol producing enzyme, CYP11B1.<\/p> As a result, high doses of Apigenin have been noted to lower cortisol levels as well as offer potential mood support benefits.<\/p> Apigenin can have many positive benefits for elderly individuals, including many of the different ones discussed in this writeup. These include Apigenin\u2019s potential prostate, blood pressure, cardiovascular, positive mood, & anti-aging benefits, and more.<\/p> In addition to those, an important thing for the elderly that often gets overlooked is the chance for a better quality of life by helping to prevent the loss of muscle tissue as each % of loss can reflect negatively on one\u2019s health and also on their self-esteem.<\/p> Apigenin has been clinically studied and shown to have promising potential to help support prostate health. This has led to Apigenin becoming one of the fastest growing ingredients in terms of popularity in this supplement category.<\/p> Apigenin may have positive benefits on cardiovascular health by supporting a reduction in blood pressure and inflammation.<\/p> Animal models have shown Apigenin to have cardioprotective effects in rats with hear damage and one study found Apigenin to protect rats against heart attacks by reducing edema, cell death, and oxidative stress.<\/p> Apigenin has the potential to have a positive benefit on a variety of neurological and mood related issues by supporting improved neuron formation and strengthening connections between brain cells.<\/p>","gtin12":"891192002336","image":["https:\/\/siteimgs.com\/10017\/item\/api-plex-rendering-front_1660228021-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/32273\/competitive-edge-labs-api-plex-90-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"33.99","url":"https:\/\/www.dpsnutrition.net\/i\/32273\/competitive-edge-labs-api-plex-90-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Competitive Edge Labs Api-Plex - 2 x 90 Capsule Bottles TWINPACK","sku":"CG2030","description":" Anabolic Phytonutrient & Muscle Builder Novel Muscle Building Supplement<\/p> Api-Plex Highlights\/Supports:<\/p> Ask Yourself a Few Questions: Do you want to build lean muscle and strength? Do you want to improve body-composition and workout performance? Do you like the idea of supplementing with an ingredient that has so many potential benefits that a series of articles could be written about it? ^^^ If so, Apigenin may be a supplement of interest to you.<\/p> The quest for muscle and performance gains has led researchers for years to look for natural compounds that can enhance muscle protein synthesis, boost muscle growth, enhance recovery, and improve performance. Over the years, scientists have come across a number of exciting natural anabolic compounds, but rarely one that has such a broad range of potential benefits as Apigenin.<\/p> Lean Muscle & Strength Improved Workout Performance Increases in Stamina & Endurance Increased Protein Synthesis Improved Insulin Resistance Supports Cortisol Modulation Enhanced IGF-1 and IGF-2 Levels Anabolic & Anti-Catabolic Properties Potential Anti-Aromatase\/Anti-Estrogenic Properties & More<\/p> Positive Mood Prostate Health Blood Pressure Support Cardiovascular Health Anti-inflammatory Support Improved Insulin Resistance Positive Effects on Autophagy Improved Sense of Well-Being Neuroprotective & Cardioprotective Properties Numerous Potential Anti-Aging & Longevity Benefits & More<\/p> For Those That Want to\u2026. Maximize Every Possible Bit of Their Natural Muscle Growth Potential<\/p> What is Apigenin? Apigenin is a natural flavonoid found in parsley, celery, chamomile, and citrus fruits that is similar to Quercetin, Hesperidin, Luteolin, and Kaempferol. However, even though its structure is very similar to these compounds, Apigenin has some very different effects in the body than those related substances.<\/p> Apigenin has a natural anabolic effect, as first discovered by researchers at the Korea Food Research Institute.<\/p> In the initial study that led to Apigenin\u2019s popularity for building muscle, scientists began experimenting with his flavone with mice and the mice receiving the Apigenin had significant muscle mass gains over the mice not receiving it. The greater the dosage of Apigenin the mice took, the larger the quad increase!<\/p> Apigenin, even before the research showing its natural anabolic benefits, was already regarded as a very exciting compound due to its wide variety of overall benefits including its anti-inflammatory benefits as well as its potential prostate, neuroprotective, and cardioprotective properties. However, of particular interest to many researchers is Apigenin\u2019s potential anti-cancer benefits, which have made Apigenin the subject of many studies around the world.<\/p> Another very exciting aspect of Apigenin is its ability to enhance autophagy. Autophagy is a natural cellular mechanism by which by which the cells in our body degrade unnecessary or damaged components within the cell. The process of autophagy helps maintain normal functioning (homeostasis) in the cell. (If you\u2019re familiar with what defragging a computer means, think of that as a good comedic analogy to this process by the cells).<\/p> Apigenin has also been studied for a wide variety of other potential benefits including its anti-inflammatory, antioxidant, anti-aromatase, cardiovascular, and antibacterial properties, and more.<\/p> Muscle Building, Longevity, Anti-Aging Properties, & More What are flavones\/flavonoids?<\/p> Flavonoids\/flavones are bioactive compounds in plants that exert a wide range of biological effects. They fulfill many different functions in plants and the ones in Apigenin have been shown to offer a wide range of potential beneficial effects, including beneficial effects on improved athletic performance and helping to build and preserve muscle tissue.<\/p> Apigenin Study Relating to Muscle Growth and Performance Enhancement: Scientists at the Korea Food Research Institute began experimenting with Apigenin in mice and found that the mice receiving Apigenin had significant muscle mass gains of the mice not receiving it.<\/p> This study was split into a control group, a lower dose Apigenin group, and a higher dose Apigenin group. Researchers observed that the greater the dose of Apigenin that the mice took, the larger the quadriceps increase.<\/p> The estimated human equivalent to the dosages used in these studies were 20 mg. for the lower dosage group and 40 mg. for the higher dosage group.<\/p> There were a number of mechanisms of action noted in the studies, including:<\/p> Apigenin increased the production of contractile muscle protein (MHC). Increases in the anabolic hormones IGF-1 and IGF-2. Increases in PGC-1-alpha, a signal molecule that stimulates cells to manufacture more mitochondria. Triggering of anabolic pathways by activating the enzyme protein arginine methyltransferase-7 (Prmt7) \u2013 shown after in vitro research with C2C12 muscle cells.<\/p> Some things mentioned in researcher\u2019s conclusions were:<\/p> \u201cWe found that apigenin increases quadriceps muscle weight in mice and increases their running distance on an accelerating treadmill.\u201d \u201cThese events are attributable to upregulation of the Prmt7-PGC-1-alpha-GPR56 signaling pathway.\u201d \u201cWe also found that apigenin induces myogenic differentiation by regulating Prmt7-p38-myoD and the Akt-S6K1 pathway in C2C12 cells.\u201d \u201cThese results suggest that apigenin could be used as a functional food to prevent muscle loss and enhance muscle function.\u201d<\/p> We found during our own research on this that the links may change depending on the one provided to this study, but can be found by doing a google search with the terms \u2018Korea Food Research\u2019 and \u2018Apigenin\u2019.<\/p> Muscle Mass\/Lean Muscle Gains and Performance Enhancement:<\/p> As mentioned above, Apigenin was shown in studies to increase protein synthesis and the same researchers observed substantial muscle growth. These researchers noticed observable increases in muscle size and function, including increased thickness in the quadriceps muscles and increased running performance.<\/p> When compared to the control group, the higher the dose of Apigenin, the greater the increase in muscle mass. It is also important to note that these increases in muscle size came without increases in total body weight or subcutaneous fat gain.<\/p> In addition to increased protein synthesis, researchers noted that these muscle gains were due to enhanced myogenic differentiation, increases in the nucleus ratio in muscle fibers (myotubes), and increased phosphorylation of p38 MAPK. This is significant because p38 MAPK is a major regulator or skeletal muscle development.<\/p> This makes Apigenin an extremely attractive potential natural muscle building compound.<\/p> In studies on mice, after 7 weeks of Apigenin supplementation, researchers let mice run to exhaustion on a treadmill. The ones that had received Apigenin performed better than the ones in the control group. Rodent studies don\u2019t always correlate directly to humans but real world feedback on Apigenin supports the theory that Apigenin may significantly improve stamina and athletic performance in many individuals.<\/p> Apigenin has a lot of potential as an anti-aging & longevity supplement for a variety of reasons, many of which are discussed above or below in this write up and range from its potential overall anti-cancer benefits to its cardiovascular, cardioprotective, and neuroprotective benefits, and more.<\/p> In addition to the ones listed above, Apigenin has the potential to be a potent anti-catabolic (muscle preserving) supplement to help fight the muscle wasting effects of aging.<\/p> The importance of maintaining strength and muscle mass is often overlooked in the scope of most anti-aging supplements, but it can be extremely important for a wide variety of reasons including supporting immune system health, injury prevention, improved mobility & stability, improved self-esteem, and more.<\/p> The mTOR pathway is the pathway in the body that drives muscle protein synthesis. It can be activated by a number of means including by amino acids (leucine), insulin, and various growth factors.<\/p> Apigenin has been reported to significantly increase muscle protein synthesis via increased phosphorylation of several key components in the mTOR pathway, including Akt, S6K1, and 4E-BP1.<\/p> Apigenin also supports the increased expression of protein Prmt7, a potent regulator of muscle mass.<\/p> As mentioned above, there are a number of growth factors capable of stimulating mTOR in the body. Insulin-like growth factor (IGF) is one of these growth factors. Both subtypes of IGF, both IGF-1 and IGF-2, contribute to regulating skeletal muscle development and regeneration (building muscle).<\/p> Apigenin has been shown to support the up-regulatory expression of both IGF-1 and IGF-2 in studies<\/p> Apigenin has been researched for its anti-aromatase and estrogen-modulating properties; including being studied for its effects on aromatase mRNA gene expression.<\/p> Aromatase is the enzyme that catalyzes the conversion of testosterone to estradiol (an estrogen). By supporting the reduction of both aromatase and 17\u03b2-hydroxysteroid dehydrogenase (17\u03b2-HSD), Apigenin may also support an increase in natural testosterone levels.<\/p> Apigenin\u2019s unique ability to inhibit 17\u03b2-HSD is very rare and is something that has only been accomplished naturally with very few other flavonoids.<\/p> Cortisol is the body\u2019s primary stress hormone released when we encounter threatening and stressful situations. While some cortisol is necessary and even beneficial, chronically elevated levels of cortisol can lead to significant reductions in testosterone, loss of muscle tissue, and fat storage.<\/p> Apigenin may have a beneficial effect on reducing cortisol levels. In cell culture studies using human adrenal cells, reductions in cortisol levels were noted when exposed to Apigenin. Also, Apigenin may have an inhibitory effect on a key cortisol producing enzyme, CYP11B1.<\/p> As a result, high doses of Apigenin have been noted to lower cortisol levels as well as offer potential mood support benefits.<\/p> Apigenin can have many positive benefits for elderly individuals, including many of the different ones discussed in this writeup. These include Apigenin\u2019s potential prostate, blood pressure, cardiovascular, positive mood, & anti-aging benefits, and more.<\/p> In addition to those, an important thing for the elderly that often gets overlooked is the chance for a better quality of life by helping to prevent the loss of muscle tissue as each % of loss can reflect negatively on one\u2019s health and also on their self-esteem.<\/p> Apigenin has been clinically studied and shown to have promising potential to help support prostate health. This has led to Apigenin becoming one of the fastest growing ingredients in terms of popularity in this supplement category.<\/p> Apigenin may have positive benefits on cardiovascular health by supporting a reduction in blood pressure and inflammation.<\/p> Animal models have shown Apigenin to have cardioprotective effects in rats with heart damage and one study found Apigenin to protect rats against heart attacks by reducing edema, cell death, and oxidative stress.<\/p> Apigenin has the potential to have a positive benefit on a variety of neurological and mood-related issues by supporting improved neuron formation and strengthening connections between brain cells.<\/p>","gtin12":"891192002336","image":["https:\/\/siteimgs.com\/10017\/item\/api-plex-twin_1662052616-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/32323\/competitive-edge-labs-api-plex-90-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"63.95","url":"https:\/\/www.dpsnutrition.net\/i\/32323\/competitive-edge-labs-api-plex-90-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Competitive Edge Labs BASIS","sku":"CG041","description":" <\/span><\/strong><\/p> Highlights\/Supports:<\/p>\r\n BASIS takes a very unique approach to helping you build muscle.<\/p>\r\n BASIS supports muscle building and fat loss through many of the more well-known pathways but goes a huge step further by supporting the enhancement of specific Bone Morphogenetic Protein (BMP) levels.<\/p>\r\n BASIS is an ultra-potent natural anabolic recomposition catalyst that contains 12 active ingredients including 7 branded ingredients and is designed to support an increase in the signaling, expression, and levels of specific Bone Morphogenetic Proteins (BMP’s) in order to help you build lean muscle, increase strength, enhance recovery, and improve fat loss.<\/p>\r\n ^^^ If you answered yes to any of the above questions, then meet your new workout partner, BASIS.<\/p>\r\n BASIS is designed to help you look better, feel better, and perform better (in more ways than one).<\/p>\r\n BASIS is a true multi-faceted natural anabolic muscle builder and recomposition catalyst that works through multiple pathways in order to help you reach your physique, strength, and athletic goals.<\/p>\r\n When you think of a structure, you likely think of a building. A building may be short, tall, big, or small – but no matter what the shape and size, it is only as solid as its foundation.<\/p>\r\n When you think of infrastructure, most people likely think of roadways, communications systems, power grid, water systems – all of the things that are at the very heart and core of the basic operations of our society.<\/p>\r\n The actual definition is – the basic physical and organizational structures and facilities (buildings, roads, power supplies) needed for the operation of a society or an enterprise.<\/p>\r\n Most everyone has seen a movie in which the bad guys plan involves knocking out the infrastructure of somewhere so that it negatively impacts the population.<\/p>\r\n With the above thoughts and definitions in mind, what is the foundation of the body?<\/p>\r\n The human body is made up primarily of bone and muscle tissue – they are the foundations of the human body in simplest terms.<\/p>\r\n Of course, this subject can get very deep and complex, and we could delve into the more advanced science of cells, hormones, neurotransmitters, etc. but that would be like breaking down the thought process of a buildings foundation to concrete, bricks, etc. All of these things come together to build a solid foundation, a solid structure, and contribute to a solid infrastructure.<\/p>\r\n Remember, if the foundation or infrastructure is weak, everything built on top of it is weak too.<\/p>\r\n BASIS delivers a lot of muscle building potential from a lot of different angles.<\/p>\r\n BASIS covers a lot of the popular muscle building bases but is also designed to target optimal muscle growth by opening up a variety of new muscle building pathways.<\/p>\r\n The human body is in a constant state of muscle protein turnover, meaning that it is always breaking down and rebuilding muscle tissue, a process that is crucial for muscle growth and repair.<\/p>\r\n The word anabolic is so overused that its easy to become desensitized to it and what it really means.<\/p>\r\n Here are some important definitions:<\/p>\r\n BASIS contains a variety of natural <\/span>anabolic<\/strong> <\/span>ingredients (ingredients that promote anabolism) in order to help you stay in an <\/span>anabolic state<\/strong> <\/span>(state in which the body is focused on building and repairing muscle tissue) as much as possible, by promoting <\/span>anabolism<\/strong> <\/span>(the process where the body builds and repairs muscle).<\/p>\r\n A catabolic state is essentially the opposite of an anabolic state and is a state that you would prefer to avoid as much as possible if your goal is to gain or retain lean muscle.<\/p>\r\n BASIS contains multiple ingredients that have anti-catabolic properties to help you build and retain lean muscle tissue.<\/p>\r\n Here are some important definitions:<\/p>\r\n BASIS contains a variety of <\/span>anti-catabolic<\/strong> <\/span>ingredients (ingredients that help reduce the breakdown of muscle tissue) in order to help you stay out of a <\/span>catabolic state<\/strong> <\/span>(state in which your body is breaking down muscle tissue) as much as possible, in favor of an <\/span>anabolic state<\/strong> <\/span>(state in which your body is focused on building and repairing muscle tissue.<\/p>\r\n The immune system is a complex system that helps the body fight off disease and infections in order to support optimal health.<\/p>\r\n Many people don’t think about the importance of a healthy immune system for supporting optimal muscle growth, but that can be a big mistake a lot of times.<\/p>\r\n Think about how long and hard you work to build lean muscle and strength gains, but then how quickly they can be lost during even a simple sickness or illness.<\/p>\r\n But it goes beyond that because the immune system may play an important role in lean muscle gains, exercise-related injuries and recovery, muscle loss, age-dependent muscle loss, & more.<\/p>\r\n BASIS contains ingredients to help support a healthy immune system for a strong muscle building foundation.<\/p>\r\n Bone health is of crucial importance for maximizing both lean muscle and strength gains.<\/p>\r\n Bone health can affect your results in the gym in the obvious way in that a broken bone can be detrimental to your process and keep you out of the gym for months or in some cases years.<\/p>\r\n And of course, strong bones are important for increased strength gains and injury prevention.<\/p>\r\n Years of hard fought for gains can disappear so quickly, yet many people never think about the importance of focusing on bone health as part of their foundation on which other gains are built upon.<\/p>\r\n Something very exciting about this is that there has been a lot of research in the last decade showing that some of the same growth factors that can influence bone health may also have major muscle building implications (more info below).<\/p>\r\n Senescent cells, also known as “zombie cells”, are cells that have stopped dividing but remain alive. They accumulate in the body and can release harmful substances that can contribute to aging, age-related health problems, and have detrimental effects on muscle, strength, endurance, and performance.<\/p>\r\n Muscle tissue is made up of a network of cells. These cells are constantly dividing and regenerating in order to maintain the health and function of the muscle tissue. However, at a certain point, these cells may stop regenerating and become senescent – which means that the cell is no longer a functioning part of the muscle tissue, but instead of ‘dying’ and being replaced by a healthy cell, it stays there taking up space where a healthy and contributing cell could be.<\/p>\r\n The higher the number of senescent cells in a tissue, the lower rate the tissue can perform.<\/p>\r\n To help you better understand senescence and the importance of senescent cell clearance in simple terms, think of it like defragging a computer or rebooting a phone – getting rid of the clutter and things that are slowing it down and making it not perform the way it is capable of:<\/p>\r\n If you think back to our definitions and discussion on establishing a solid infrastructure, you can likely understand why promoting senescent cell clearance is an important part of a solid foundation.<\/p>\r\n Younger\/newer muscle cells typically work harder and recover faster than older muscle cells because they have higher mitochondria counts, which may produce more energy and have greater ATP energy production capacity, leading to higher levels of cellular energy and endurance.<\/p>\r\n BASIS contains multiple ingredients that help support senescent cell clearance, including Senactiv®, the first senolytic sportsceutical that has been shown in studies to elevate exercise endurance, recovery, and energy while supporting senescent cell clearance and new muscle cell generation during high-intensity exercise.<\/p>\r\n By incorporating ingredients that have been shown in human clinical studies to support senescent cell clearance in muscle tissues, it helps lay the proper foundation for improved Bone Morphogenetic Protein (BMP) signaling, expression, and levels to deliver the best results.<\/p>\r\n Bone Morphogenic Proteins (BMPs) are a group of proteins within the Transforming Growth Factor beta (TGF-beta) super family of genes that have pivotal roles in the regulation of bone induction, maintenance, and repair. Originally discovered and researched for their ability to induce the formation of bone and cartilage, BMPs have now been found to constitute a group of morphogenetic signals that influence tissue architecture throughout the body.<\/p>\r\n Although Bone Morphogenic Protein (BMP) sounds like it would be specifically related to bones, it is not.<\/p>\r\n Research has shown that BMPS can play an important role in body-composition, both in building muscle and in reducing body-fat.<\/p>\r\n BASIS contains ingredients to help target key aspects of this exciting & complex system.<\/p>\r\n When it comes to building muscle, losing fat, improving recovery, and recovering from injuries, there is so much going on inside our bodies that we can’t see with the naked eye.<\/p>\r\n A group of powerful proteins known as Bone Morphogenetic Proteins (BMPs) plays a crucial role in many of these processes. While BMPs were originally recognized for their role in bone formation and healing, newer research has shown that they can also promote muscle growth, improve fat metabolism, and speed up recovery.<\/p>\r\n Bone Morphogenetic Proteins (BMPs) are a group of growth factors that belong to a family of proteins called TGF-beta (transforming growth factor-beta).<\/p>\r\n While the name “Bone Morphogenetic” suggests their primary function is related to bones, these proteins are involved in more than just bone growth—they play significant roles in muscle tissue repair, fat metabolism, and healing after injury.<\/p>\r\n Bone Morphogenetic Proteins (BMPs) have been found to play a crucial role in muscle anabolism, promoting muscle growth and inhibiting muscle wasting.<\/p>\r\n In simple terms, BMPs act as ‘messengers’ that tell cells in our body how to behave. They help:<\/p>\r\n Important definitions:<\/p>\r\n While BMPs are involved in many processes in the body, their impact on muscle building, fat loss, and recovery is especially important for anyone looking to improve their fitness, health, or athletic performance.<\/p>\r\n There are over 20 different bone morphogenetic proteins, each with different roles in the body.<\/p>\r\n Some of the most important BMPs when it comes to building muscle, losing fat, and recovery are:<\/p>\r\n With that in mind, let’s look at which ingredients in BASIS have been shown to increase the levels, signaling, or expression of:<\/p>\r\n It’s important to emphasize that even if you have taken some of these ingredients individually by themselves in the past, the real power is taking them together in order to effectively target the different BMP pathways together.<\/p>\r\n In the section above, we listed out which ingredients are thought to work via which Bone Morphogenetic Protein (BMP) pathways, but there’s great news – because as great as it is that BASIS works through key BMP pathways, there’s a lot more to BASIS!<\/p>\r\n Almost every ingredient in BASIS is included because it helps support building muscle &\/or burning fat via more than one pathway, and in most cases, these pathways come together to compliment each other and help provide increased synergistic results!<\/p>\r\n Icariin is derived from Horny Goat Weed (Epimedium). There are numerous standardizations available, but for the purposes of inclusion in BASIS, we selected the ultra-potent HG20X™ 20% Icariin extract.<\/p>\r\n This is a great example of an ingredient that has become so well-known for one subject or category that people often overlook any other potential benefits that it may have.<\/p>\r\n The Importance of Standardization (Icariin):<\/strong><\/span><\/p>\r\n As with many herbs, it’s not the herb itself that provides the benefits, but the active constituent that the herb is standardized for.<\/p>\r\n The active constituent of Horny Goat Weed (Epimedium) that provides the benefits is Icariin.<\/p>\r\n The active ingredient related to the bone morphogenetic protein aspect is Icariin.<\/p>\r\n So what matters is the amount of Icariin in the product.<\/p>\r\n That’s why we use HG20X™, a Horny Goat Weed standardized for a minimum 20% Icariin.<\/p>\r\n Beware – Icariins and Icariin are Very Different: <\/span><\/strong><\/p>\r\n It is very important to distinguish between Icariin and Icariins, as the (s) at the end makes all the difference. You want Icariin without the (s) at the end, as it is Icariin that provides the benefits whereas Icariins do not.<\/p>\r\n Unfortunately, many Horny Goat Weed products on the market are not standardized at all or are standardized for Icariins, as that is a lot cheaper than being standardized for Icariin. This allows for brands to significantly cut product costs, but is deceptive towards consumers, as most consumers don’t know the difference and what they should be looking for.<\/p>\r\n Sexual Health & Libido: <\/span><\/strong><\/p>\r\n Icariin supports an increase in natural testosterone levels and libido\/sex drive and has also been shown to support improved erection quality by acting as a natural PDE5 inhibitor, meaning that it may help inhibit the protein phosphodiesterase 5 enzyme that interferes with blood flow to the penis.<\/p>\r\n Enhanced Nitric Oxide\/eNOS Production:<\/span><\/strong><\/p>\r\n Icariin has been shown to increase nitric oxide (NO) production by stimulating endothelial nitric oxide synthase (eNOS) and activating signaling pathways like PI3K\/Akt. This plays a role in promoting blood flow and nutrient delivery to muscle tissues and can support improved muscle endurance, faster muscle recovery, and increased muscle fullness, pumps, and vascularity.<\/p>\r\n
\r\nFat Loss & Enhanced Body-Composition:<\/span><\/strong><\/h3>\r\n
\r\nPumps & Muscle Fullness:<\/span><\/strong><\/h3>\r\n
\r\nExciting & Novel Natural Anabolic Pathways:<\/strong><\/span><\/h2>\r\n
\r\n
\r\nOlfactory Receptors:<\/span><\/strong><\/h3>\r\n
\r\nWhat are Olfactory Receptors?<\/span><\/h4>\r\n
a-Cedrene & the Olfactory Receptors:<\/span><\/h4>\r\n
\r\ncAMP (Cyclic Adenosine Monophosphate):<\/span><\/strong><\/h3>\r\n
\r\nMuscle Building:<\/span><\/strong><\/h4>\r\n
Fat Loss:<\/span><\/h4>\r\n
Healthy Aging:<\/span><\/h4>\r\n
\r\nA note about increasing cAMP:<\/span><\/strong><\/h4>\r\n
\r\nStacking & Synergy:<\/strong><\/span><\/h4>\r\n
Hardcore Natural Anabolic<\/h5>
Anabolic Effect Highlights:<\/h5>
Let\u2019s Examine the Ingredients:<\/h5>
Korean Mistletoe:<\/h6>
Eriobotrya Japonica Extract:<\/h6>
Rehmannaie Radix Extract:<\/h6>
PrimaVie Shilajit Extract (50% Fulvic Acid):<\/h6>
ActiGin:<\/h6>
S7:<\/h6>
AstraGin:<\/h6>
Hardcore Natural Anabolic<\/h5>
Anabolic Effect Highlights<\/h6>
Let\u2019s Examine the Ingredients<\/h5>
Apigenin Potential Muscle Building & Performance Enhancing Highlights\/Supports:<\/h5>
Apigenin Potential General Health Related Highlights\/Supports:<\/h5>
Let\u2019s Examine Some More of Apigenin\u2019s Potential Benefits:<\/h5>
Muscle Mass\/Lean Muscle Gains and Performance Enhancement:<\/h6>
Stamina & Athletic Performance:<\/h6>
Anti-Aging & Longevity:<\/h6>
Apigenin \u2013 Effect on Protein Synthesis:<\/h6>
Apigenin \u2013 Effect on IGF-1 & IGF-2:<\/h6>
Anti-Aromatase Properties:<\/h6>
Cortisol Modulation:<\/h6>
Apigenin and the Elderly:<\/h6>
Prostate Health Benefits:<\/h6>
Cardiovascular Benefits:<\/h6>
Neuroprotective Benefits:<\/h6>
Apigenin Potential Muscle Building & Performance Enhancing Highlights\/Supports:<\/h5>
Apigenin Potential General Health Related Highlights\/Supports:<\/h5>
Api-Plex<\/h5>
Let\u2019s Examine Some More of Apigenin\u2019s Potential Benefits:<\/h5>
Stamina & Athletic Performance:<\/h5>
Anti-Aging & Longevity:<\/h5>
Apigenin \u2013 Effect on Protein Synthesis:<\/h5>
Apigenin \u2013 Effect on IGF-1 & IGF-2:<\/h5>
Anti-Aromatase Properties:<\/h5>
Cortisol Modulation:<\/h5>
Apigenin and the Elderly:<\/h5>
Prostate Health Benefits:<\/h5>
Cardiovascular Benefits:<\/h5>
Neuroprotective Benefits:<\/h5>
Lean Muscle Growth Stimulator<\/span><\/strong><\/h2>\r\n
Natural Anabolic Recomposition Catalyst<\/span><\/strong><\/h2>\r\n
Lean Muscle, Strength, Fat Loss, & More<\/span><\/strong><\/h2>\r\n
BASIS<\/h3>\r\n
\r\n
\r\nMulti-Action Muscle Building & Natural Anabolic Pathway Support: <\/strong><\/span><\/h4>\r\n
\r\n
\r\nAsk Yourself a Few Questions:<\/span><\/strong><\/h4>\r\n
\r\n
\r\n
\r\nBASIS<\/strong> – Building A Solid Infrastructure<\/strong><\/span><\/h3>\r\n
\r\n
\r\nStructure:<\/strong><\/span><\/h5>\r\n
\r\nInfrastructure:<\/strong><\/span><\/h5>\r\n
\r\nBuilding a Solid Infrastructure:<\/strong><\/span><\/h5>\r\n
\r\nB.A.S.I.S. – Not Just Another Average Natural Anabolic Muscle Builder:<\/strong><\/span><\/h5>\r\n
\r\nPathways to a Solid Infrastructure:<\/strong><\/span><\/h3>\r\n
\r\n
\r\nAnabolic Pathways <\/strong><\/span>–<\/span> <\/span>Maximizing Muscle Growth:<\/span><\/strong><\/h4>\r\n
\r\n
\r\nAnti-Catabolic Pathways <\/strong><\/span>–<\/span> <\/span>Minimizing Muscle Breakdown:<\/span><\/strong><\/h4>\r\n
\r\n
\r\nImmune System:<\/span><\/strong><\/h4>\r\n
\r\nBone Health:<\/span><\/strong><\/h4>\r\n
\r\nSenescent Cell Clearance:<\/span><\/strong><\/h4>\r\n
\r\n
\r\nBone Morphogenic Proteins:<\/span><\/strong><\/h4>\r\n
\r\nBone Morphogenetic Proteins (BMPs) – A Better Understanding <\/strong><\/span><\/h3>\r\n
\r\n
\r\nWhat are Bone Morphogenetic Proteins (BMPs)?<\/span><\/strong><\/h4>\r\n
\r\n
\r\n
\r\nKey BMP’s Involved in Muscle Growth, Fat Loss, & Recovery:<\/span><\/h4>\r\n
\r\n
\r\n
\r\nImportant Note:<\/span><\/strong><\/h5>\r\n
\r\nLet’s Examine the Ingredients:<\/strong><\/span><\/h3>\r\n
\r\n
\r\nIcariin (from Horny Goat Weed) (as HG20X™) – 500 mg. HGW\/100 mg. Icariin<\/span><\/strong><\/h4>\r\n
\r\n
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